Southern Medical Journal - Antinuclear Antibody–Negative, Drug-Induced Lupus Caused by Lisinopril.
ABSTRACT: The clinical symptoms of drug-induced lupus (DIL) are similar to those of idiopathic systemic lupus erythematosus. The literature indicates that in patients with DIL, sera generally contain antinuclear antibodies (ANAs); however, ANA-negative DIL has been reported. The list of medications implicated as etiologic agents in DIL continues to grow.
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This list includes two different types of angiotensin-converting enzyme inhibitors–captopril and enalapril. We report the first case of DIL caused by lisinopril. Our patient had negative results on ANA testing and had histone …
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